Some new and exciting research has been done recently by researchers at Indiana University. Others involved in the research include the German Research Center for Environmental Health. These two groups combined have been able to cure lab mice of adult onset diabetes, obesity, and all abnormalities that occur with lipid balance with improved glucose sensitivity. Other benefits of their treatment include enhanced caloric burning and also a lower appetite. The specific treatment is a new peptide that is a molecular integration of the hormones designed to target the gastrointestinal system. The peptide combines two important hormones in the endocrine system GIP and als GLS-1. It also now includes glucagon in the treatment which is what has drastically improved the results. These hormones have proven to lower the lab rats’ blood sugar levels and also reduce their fat levels to a level that is far better than any previously created treatment. It seems as though these three hormones have a synergistic affect on the body.
Part of the success comes from the three hormones placed in a single molecule. As a result several metabolic factors are affects at the same time. Areas that are primarily targeted with this treatment include the brain, liver, fat, and pancreas. During the trials the researchers found they were able to reduce the body fat in the rats by about 30%. This is significantly more than when the researchers had attempted using the treatment without the glucagon add on. The great thing about this specific molecule is it can perform the actions of three hormones. While the GLP-1 and the GIP primarily work towards improving the action of insulin and lowering blood sugar levels, GLP-1 is well known for reducing hunger, and glucagon also helps improve the long term rate at which calories are burned.
It is also important to note that clinical trials with humans has already begun. This is good news for a large percentage of people in the United States because we have the second highest rate of obesity out of all the nations. Because of our high rate of obesity in the USA we also have a high level of the older population that have adult onset diabetes. Once the body has been programmed to maintain a certain weight it can be very difficult to lose weight even with proper diet and exercise. This new treatment brings hope to those who have failed at losing weight on their own. As a paramedic EMT I constantly take care of patients with adult onset diabetes. Most people don’t realize how detrimental obesity and adult onset diabetes can be to their health. The large majority of the people I have to perform the skills learned in ACLS certification and BLS certification are those that are overweight and many of which have adult onset diabetes. As technology improves we will see increased treatments that can help individuals manage their health issues and overcome specific factors that can dramatically cut down their life-span. This is just one of many diet and glucose regulating treatments on the horizon that will dramatically impact the general health of the American nation.
Several prestigious universities have performed a research study that has now linked the sense of well-bing and purpose to result in a longer lifespan. While testing in the past has proven benefits of those who have a positive outlook on life at advanced ages, now researchers can definitively say that there is a link between improved physical function and that of subliminal positive messaging. The study included over nine thousand individuals. Each with an age of 65 or older. Each individual was then divided into a group that labeled them as having a higher or lower level of well-being. After the subject group was created the researches then looked at the group approximately 8 years later to determine their overall health and physical function.
To determine which well-being group each individual belonged the researchers used questionnaires and then put the individuals into a broad set along with those that relatively matched on the same criteria. Ultimately the groups were made into 4 large subsets of individuals ranking their overall well-being. Each group had to be adjusted for other influencing factors from current physical health, sex, lifestyle habits, along with many others. Each member was measured on three different groups or types of well being. One of these being “eudemonic well-being,” which is the sense of value one adds to society and life around them. Another of these is “hedonic well-being” which is a sense of ambiguous happiness or ambiguous negative feelings and thoughts. The final one they measured was “evaluative well-being” which is the level of satisfaction one has with what they have in life. The findings were actually quite astonishing to the researchers showing that those with a higher sense of well-being lived an average of two whole years longer than those that suffered from a lower level of purpose and well being. The final statistics showed that after the 8 years out of those with the lower level of well-being 29 percent of them had already died while in the group of those with the higher level of purpose and well-being had only 9 percent of their group die.
The statistics of the percentage of people who have high levels of life satisfaction and well-being is quite different among cultures and countries. Those in English speaking countries tend to have the highest level of sense of well-being in their later years compared to most other countries. Those in Russia tend to have some of the lowest levels of a sense of well-being in their advanced years. Something to study next would be why each culture or country may have these differences and how we may learn from some cultures to help improve the sense of well-being of those who live in a country and culture where many individuals of advanced age aren’t happy or satisfied with their life. One of the simple answers to this is about involvement in the world around you. Those with advanced age that stay more involved with friend groups, social circles, or activities generally have a much higher level of well-being compared to those that are isolated. Here in the United States many people of advanced age have both the wealth and access to the infrastructure to make that happen. Hopefully these studies will lead to government involvement in helping to provide the resources in other countries to those who are of advanced age. In the long run it may actually reduce the cost burden of taking care of the sick geriatric population if they are kept in better mental health and stimulated socially.
While becoming an emergency medical technician (EMT) isn’t necessary an easy task, the process can be simplified if you know what you’re doing. You never want to go into an education blind. An education requires time and money so spending your money in the right places is extremely important when choosing a career path. I decided to become an EMT almost 10 years ago and fortunately I had a lot of people that had gone through the process to coach me along the way. My dad is an Emergency Room doctor so he worked with several firefighter EMTs that were able to give me good advice when I was thinking about following in their footsteps. 1) Find Someone Who Has Already Become an EMT This is one of the smartest things you can do when deciding on an education and probably my single best piece of advice. I can give you all the tips in the world but there are certain nuggets of knowledge about schools and other jobs in your area that are known to the EMTs in your area. Most EMTs I have known are extremely friendly and supportive of anyone that wants to follow in their footsteps. Many of them made mistakes along the way when going through their scholastic and practical training. Because of this they can help you avoid certain pitfalls or mistakes that they or their friends made in the past. 2) Shadow an EMT in Your Area Before you go through the long and tedious effort to become educated and licensed as an EMT you should first know if it is even something that you would enjoy doing. Managing patient’s in a live situation verses watching a television series based on emergency scenarios in a hospital are very different. Also, when applying for EMT schools they will notice if you have any past experience shadowing. Many schools even require you to shadow an EMT a few times before they will accept you. 3) Build a List of Schools and Requirements You need to educate yourself regarding the different EMT schools in your area. Also, once you have these schools listed it is even more important that you list their requirements for entry into their programs. Sometimes different schools have different requirements. If three out of four schools have similar requirements regarding classes than you know where you can most efficiently use your time when completing pre-requisites. You may want to disregard a school that has several required courses that are not required by other schools. 4) Contact the Schools Contacting the schools before you begin the pre-requisites is also extremely important. You will want to know what the average GPA was for the previously accepted class. You will also want to find out what they view as most important in a candidate. Just by making a couple phone calls you can greatly improve your understanding of what you need to do to become an EMT. 5) Earn your ACLS, PALS, and BLS certification before entering into any program. ACLS online renewal is one of the easiest ways to complete this. Generally you can take your ACLS online renewal course in under an hour. PALS certification and BLS certification can also usually be earned in under an hour online. If you do these courses in a live classroom they will take several days to complete. While the online courses don’t have a hands on skills test I honestly don’t believe that the skills of resuscitation are learned in a 5 minute demo. It takes real life experience over and over again while being surrounded with other professionals to become proficient in CPR.
From the time anti-cancer drugs are publicized to when they are actually deliverable products to the masses is quite a long one. Most people are not familiar with this process and what these drugs must face before being delivered to market. Many of these drugs actually never make it past clinical trials. The process is long and requires the attention and investment of many types of professionals from regulating agencies, research and developers, healthcare workers, buyers, and also patients. These are just some of the people involved in bring a new anti-cancer drug to market. Regulatory approval is not an easy thing to obtain in the medical industry. There are a series of trials that first must be run to evaluate the efficacy and risk of each new medication that is presented. Animal trials must first be performed. These animal trials often start with rats and move up to pigs and other primates. Once these drugs show to be relatively safe and have promise in eliminating cancer they can then be performed on a very small human population that are closely monitored and evaluated. For a drug to prove to be safe enough for regular human use commonly takes up to seven years of research, development, and clinical trials. Drug companies spend billions of dollars in the development of new drugs to bring them to market. Once the drug proves successful and is approved for human use on large scale it now must be brought to the attention of practicing physicians so they begin to use the medicine in practice. The process to have a drug completely implemented into practice by physicians efficiently and successfully usually takes about three years once the drug is finally approved. Unfortunately this delay in the creation of a drug and it’s availability is primarily for the safety of those who could possibly use it. Some people who might actually be able to take advantage of some of these drugs and live are denied the privilege because the drug hasn’t gone through the appropriate testing and approval. Some people even go to the extreme to travel to distant countries that don’t have the same tight regulations like the United States to obtain specific drugs and treatments that won’t be made legal in the USA until several years later. Those that suffer from a life-threatening illness such as advanced or late stage cancer find that this option is a viable option because they don’t have much to lose. Many of the healthcare providers I work with often talk about their patient’s that have used foreign medical aid to help in the even of life threatening illness. My ACLS online certified friends and I each make an effort to save the lives of those in the end stages of life but we have limits to what we are capable and legally allowed to do. Recognizing what your healthcare needs are and making the appropriate sacrifices to get the best treatment available is crucial in your survival. Being familiar with the drug approval process can help you make a more informed decision regarding the health of you and your loved one.